I am broadly interested in understanding the biological control of mosquitoes and how the recombination of two microbial pathogens improves toxicity. My research direction covers a wide variety of subject areas including mosquito biology, biochemistry, molecular biology, toxicology, functional genomics and ongoing research addresses non-related toxins of mosquito densoviruses and bacterial pathogen bacillus thuriengenesis together contribute to eradicating mosquito population and management. I have contributed to total of 20 research articles including 5 as first author in this domain.

【Representative Publications】

Khadija Batool, Jie Xiao, Ye Xu, Ting Yang, Peiwen Tao, Siyu Zhao, Jiao Chen, Intikhab Alam, Yugu Xie, Jinbao Gu, Xiaoguang Chen*.Densovirus Oil Suspension Significantly Improves the Efficacy and Duration of Larvicidal Activity against Aedes albopictus. Viruses. 2022, 14:475.

Khadija Batool, Intikhab Alam, Peiwen Liu, Zeng Shu, Siyu Zhao, Wenqiang Yang, Xiao Jie, Jinbao Gu, Xiao-Guang Chen*.Recombinant Mosquito Densovirus with Bti Toxins Significantly Improves Pathogenicity against Aedes albopictus. Toxins. 2022, 14:147.

Khadija Batool, Intikhab Alam, Xiao-Qiang Yu and Lingling Zhang. CTLGA9 interacts with ALP1 and APN receptor to modulate Cry11Aa toxicity in Aedes aegypti. Journal of Agriculture and Food Chemistry 67 (32) 8896-8904 (2019).

Khadija Batool , IntikhabAlam, Guohui Zhao and Lingling Zhang. Transcriptomic Analysis of Aedes aegypti in Response to Mosquitocidal Bacillus thuringiensis LLP29 Toxin, Scientific Reports volume 8(1), 12650 (2018).

Khadija Batool , Intikhab Alam , Guohui Zhao , Xiaoqiang Yu, and Lingling Zhang. C-Type Lectin-20 Interacts with ALP1 Receptor to Reduce Cry Toxicity in Aedes aegypti, Toxins 10(10), 390 (2018).

Jin Xu, Chenxu Wu, Khadija Batool, Junmin Yao, Lingling Zhang. recG is involved with the resistance of Bt to UV. Pesticide biochemistry and physiology, 167:104599 (2020).

Guihui Zhao, Liu Jinan, Hu Xiaohua, khadija Batool, Jin Liang, Xiaoqiang Yu, and Lingling Zhang, Cloning, expression and activity of ATP-binding protein in Bacillus thuringiensis toxicity modulation against Aedes aegypti. Parasites & Vectors 12:319 (2019).

Xiaohua Hu, Hong Chen, Jin Xu, Khadija Batool, Chenxu Wu, Songqing Wu, Lingling Zhang. Function of Aedes aegypti galectin-6 in modulation of Cry11Aa toxicity. Pesticide biochemistry and physiology 162, 96-104 (2019).

Lingling Zhang, Guohui Zhao, Khadija Batool, Mingfeng Chen and Xiong Guan. Cry11Aa interacts with the ATP-Binding Protein from Culex quinquefasciatus To Improve the Toxicity. Journal of Agriculture and Food Chemistry, (10884-10890 (2017).

Ling-Ling Zhang, Xiao-Hua Hu, Khadija Batool, Munmun Chowdhury, Xiao-Qiang Yu. A. aegypti Galectin Competes with Cry11Aa for Binding to ALP1 to Modulate Cry Toxicity. Journal of Agriculture and Food Chemistry 66(51), 13435−13443 (2018).

【Scientific research projects (topics)】

China Postdoctoral Science Foundation, general funding, 2020M672715

(Topic: Using recombinant Mosquito densovirus to develop an efficient and environmentally friendly mosquito vector larvicides, 2021-01 to 2022-12, net worth 80,000 yuan).